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茶多酚对大鼠主动脉微血管样结构影响的研究
引用本文:徐力,孙韬,张燕明,陈信义.茶多酚对大鼠主动脉微血管样结构影响的研究[J].中华中医药学刊,2005,23(12):2168-2171.
作者姓名:徐力  孙韬  张燕明  陈信义
作者单位:北京中医药大学东直门医院血液肿瘤科,北京,100700
摘    要:目的:开展茶多酚对大鼠主动脉微血管样结构影响,为其抗肿瘤血管生成分子机制研究提供实验资料.方法:大鼠主动脉无血清培养,加入茶多酚大、中、小剂量及bFGF(碱性成纤维母细胞生长因子),观察对微血管结构影响.结果:茶多酚大、中、小剂量均可抑制新生血管形成.结论:茶多酚能抗血管生成.

关 键 词:茶多酚  抗血管生成  实验研究
文章编号:1009-5276(2005)12-2168-04
修稿时间:2005年6月18日

Effect of Tea Polyphenols on Microvessel Structure of Rat Aorta
XU Li,SUN Tao,ZHANG Yan-ming,CHEN Xin-yi.Effect of Tea Polyphenols on Microvessel Structure of Rat Aorta[J].Chinese Archives of Traditional Chinese Medicine,2005,23(12):2168-2171.
Authors:XU Li  SUN Tao  ZHANG Yan-ming  CHEN Xin-yi
Abstract:Objective:To investigate into the effect of tea polyphenols on the microvessel structure of rat aorta to provide pre-experimental data for the research of the mechanism of tea polyphenols in preventing tumor angiogenesis factor.Methods:Serum-free culture of the rat aorta was conducted,with large,medium and small dosages of basic fibroblast growth factor(bFGF)added,to observe its effect on the microvessel structure.Results:ifferent dosages of tea polyphenols could inhibit the formation of new vessels.Conclusion:Tea polyphenols can prevent vessel formation.
Keywords:tea polyphenols  prevent vessel formation
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