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Chemical constituents from Croton crassifolius Geisel
Authors:Junli Liu  Yanping Hao  Jianbin Wang  Wentong Dou  Chen Chen  Yan Guo  Dan Yuan  Hongzheng Fu
Abstract:Croton crassifolius Geisel belongs to the genus croton of the family euphorbiaceae. By means of solvent extraction and repeated chromatorgraphy on silica gel, Sephadex LH-20 and HPLC, the ethanol extract of the roots of Croton crassifolius Geisel was chemically investigated, which led to the isolation of nine diterpenoids. By using spectroscopic analysis, their structures were identified as follows: Crassifolin P (1), Crassifolin J (2), 1,5,6-trimethyl-5-(2-(5-oxo-2,5-dihydrofuran-3-yl)ethyl)-1,2,3,4,5,6,7,8-octahydronaphthalene-1-carboxylate (3), Penduliflaworosin (4), isoteucvin (5), Crassifolin G (6), teucvin (7), Chettaphanin I (8), mallotucin D (9). Among of them compound 1 was a new compound.
Keywords:Croton crassifolius Geisel  Chemical constituents  Structural identification  
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