南京市1996-2005年1128例肺癌住院病例发病特征的动态变化分析

背景与目的肺癌的流行病学特征是随时间的变化而不断改变的,本研究拟通过分析南京市近10年来肺癌住院病例在性别、年龄、吸烟、病理类型等方面的特征和动态变化,为肺癌病因研究提供临床资料。方法收集整理南京市胸科医院1996年-2005年10年间1128例新发肺癌住院病人的临床资料并进行统计学分析,重点比较前后5年肺癌发病特征动态变化。结果女性肺癌的比例明显逐年增加,总体男女性别比为2.4:1,其中前5年为3.2:1,后5年则下降为1.9:1。10年来肺癌的平均发病年龄呈下降趋势,且后5年小于50岁的病例数占25.6%,显著高于前5年(10.2%)。10年来肺癌病理类型中腺癌的病例数明显上升,由前5年32.4%上升到后5年的45.2%;而鳞癌的病例数有所下降,由40.6%下降到30.8%。无论男性和女性,鳞癌患者的吸烟比例最高。结论10年来肺癌的发病有年轻化的趋势,且女性、腺癌病例有明显增加,值得引起广泛的关注。

The characteristics of lung cancer cases in 1996-2005 in Nanjing, China

Background and objective Epidemiology of lung cancer has changed along with the time. The aim of this study is to analyze the distribution of sex, age, pathology and smoking in the lung cancer cases from 1996 to 2005 of Nanjing city. Methods Clinical data of 1128 lung cancer cases were collected and evaluated.Results The amount of lung cancer cases in male was more than that in female, the proportion of male and female was 2.4:1, but the cases of female were increased in 2001-2005. The average age of lung cancer incidence had a trend of decrease in these 10 years, the cases of under 50 age were increased in 2001-2005, the cases of adenocarcinoma were increased evidently in these 10 years. The smoking rate of the male was higher than the female, and the squamous carcinoma was the highest in all cases. Conclusion The lung cancer incidence age has a decreasing trend in these past 10 years. The number of females with lung cancer increases compared with males, and the proportion of adenocarcinoma shows an increase tendency in all cases.