| 扶正解毒颗粒抗镍暴露肝损伤31例临床研究 |
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| 引用本文： | 吕晓云,赵健雄,滕玉莲. 扶正解毒颗粒抗镍暴露肝损伤31例临床研究[J]. 中医杂志, 2005, 46(12): 910-912 |
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| 作者姓名： | 吕晓云 赵健雄 滕玉莲 |
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| 作者单位： | 1. 兰州大学中西医结合研究所,甘肃省兰州市东岗西路199号,730000
2. 兰州大学校医院 |
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| 摘 要： | 目的:研究扶正解毒颗粒抗镍暴露肝损伤的临床疗效及其对血镍、肝功能、血象、心电图、B超、X线的影响.方法:将60例患者随机分为两组,治疗组31例采用扶正解毒颗粒合用门冬氨酸钾镁、促肝细胞生长素治疗;对照组29例仅用门冬氨酸钾镁、促肝细胞生长素治疗,疗程均为4周.观察血清镍、肝功能及血象、心电图等变化.结果:治疗组临床疗效、降镍作用、肝功能、异常血象、X线、B超及心电图的改善均优于对照组(P＜0.05或P＜0.01).结论:扶正解毒颗粒具有显著抗镍暴露肝损伤的作用.
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| 关 键 词： | 肝疾病/中医药疗法 @扶正解毒颗粒 @肝损伤 |
| 收稿时间： | 2004-12-24 |
| 修稿时间： | 2004-12-242005-04-11 |
Clinical Study on Treatment with Fuzheng Jiedu Granule in 31 Cases of Hepatic Injury Induced by Nickel Exposure |
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| Lv Xiaoyun,Zhao Jianxiong,Teng Yulian. Clinical Study on Treatment with Fuzheng Jiedu Granule in 31 Cases of Hepatic Injury Induced by Nickel Exposure[J]. Journal of Traditional Chinese Medicine, 2005, 46(12): 910-912 |
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| Authors: | Lv Xiaoyun Zhao Jianxiong Teng Yulian |
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| Affiliation: | 1. Institute of Integrated TCM and Western Medicine, Lanzhou University, Lanzhou 730000; 2. School Hospital of Lanzhou University |
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| Abstract: | Objective:To observe the clinical therapeutic effect of Fuzheng Jiedu Granule(FJG)on hepatic injury induced by nickel exposure, and effects on serum nickel content,liver functions,blood cell,electrocardiogram,and findings of B-ultrasonography and X-ray. Methods:60 cases were randomly divided into two groups,treatment group(n=31)and control group(n=29).The treatment group were treated with FJG combined with potassium-magnesium aspartate and hepatocyte growth-promoting factor,and the control group only with potassium-magnesium aspartate and hepatocyte growth-promoting factor.All of them were treated for 4 weeks.Changes of above indexes were investigated.Results:The treatment group was superior to the control group in the therapeutic effect on symptoms and signs,and in the improvement of the above indexes(P<0.05 or P<0.01).Conclusion:FJG plays a significant role in antagonizing hepatic injury induced by nickel exposure. |
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| Keywords: | Hepatic diseases/TCM therapy @ Fuzheng Jiedu Granule @ Hepatic injury |
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