Peritumoral brain edema in intracranial meningiomas evaluated by dynamic perfusion-weighted MR imaging: a preliminary study |
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Authors: | Uematsu Hidemasa Maeda Masayuki Itoh Harumi |
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Institution: | (1) Department of Radiology, Fukui Medical University, Fukui, Japan,;(2) Department of Radiology, Mie University School of Medicine, Mie, Japan,;(3) Present address: Department of Radiology, University of Pennsylvania Medical Center, 3600 Market Street, Suite 370, Philadelphia, PA 19104–2649, USA, |
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Abstract: | Our objective was to semi-quantitatively evaluate the cerebral perfusion in the peritumoral brain edema of meningiomas using
dynamic perfusion-weighted MR imaging. Six patients with intracranial meningiomas accompanied by peritumoral brain edema were
prospectively examined by perfusion-weighted MR imaging. One patient was examined twice, once before and once 5 months after
the surgical resection. The relative regional cerebral blood volume (rrCBV), the relative regional cerebral blood flow (rrCBF),
and the relative regional mean transit time (rrMTT) were calculated for peritumoral brain edema and the contralateral white
matter. These parameters were compared between peritumoral brain edema and the contralateral white matter. The time–concentration
curve of the peritumoral brain edema was less prominent than that of the contralateral white matter, resulting in a significantly
lower rrCBV (mean 46%) and rrCBF (mean 45%) in peritumoral brain edema than those of contralateral white matter. The serial
perfusion-weighted MR imaging also demonstrated the recovery of these parameters after the removal of meningioma by means
of surgical resection. Perfusion-weighted MR imaging can demonstrate significantly decreased rrCBV and rrCBF in peritumoral
brain edema compared with those in normal white matter.
Electronic Publication |
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Keywords: | Peritumoral brain edema Meningiomas Perfusion-weighted MR imaging Double echo MRI |
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