Delayed Hemolytic Transfusion Reaction Associated with Rh Antibody Anti-f: First Reported Case |
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| Authors: | Dr. Robert A. O''Reilly Charles M. Lombard and Raymond L. Azzi |
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| Affiliation: | Departments of Medicine and Pathology, Santa Clara Valley Medical Center, San Jose, and Stanford University School of Medicine, Stanford, Calif., USA |
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| Abstract: | A delayed hemolytic transfusion reaction (DHTR) occurring in a 30-year-old Caucasian man is described. His blood groups were B, CDe/cDE (R1R2, f-) K-, S-s+, Fy (a + b-), and Jk (a + b +). Eight days after receiving two units of packed red blood cells, his urine was strongly positive for hemoglobin; serum-free hemoglobin was 125 mg/dl. Serum contained a clearly reactive Rh antibody of anti-f specificity and a weakly reactive anti-Kell. The DHTR was probably caused by an anti-f alloantibody appearing as an anamnestic response to transfusion of seemingly compatible, but f-positive blood. |
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