电针对急性高血压大鼠肾上腺素和去甲肾上腺素的影响

目的观察电针对急性高血压大鼠的降压作用。方法36 只Wistar 雄性大鼠随机分为对照组(n=8)、模型组(n=8)、药物组(n=10)和电针组(n=10)。应用肾上腺素法制备急性高血压大鼠模型，电针百会和足三里穴，测定电针后各组血压的变化以及血清肾上腺素和去甲肾上腺素的变化。结果药物组和电针组大鼠收缩压和舒张压均低于模型组(P<0.05)，且两组疗效无显著性差异(P>0.05)。模型组血清肾上腺素和去甲肾上腺素水平高于对照组(P<0.05)，电针组与药物组血清肾上腺素和去甲肾上腺素水平低于模型组(P<0.05)。结论电针百会和足三里可能通过降低血中肾上腺素和去甲肾上腺素来降低急性高血压大鼠的血压水平。

Effects of Electroacupuncture on Adrenalin and Noradrenalin Levels of Acute Hypertension Rats

Objective To explore the effects and mechanism of electroacupuncture on acute hypertension in rats.Methods 36 male Wistar rats were randomly divided into control group(n=8),model group(n=8),drug group(n=10) and electroacupuncture group(n=10).The acute hypertension rat model was induced with injecting adrenalin into abdomen.Blood pressure was measured and blood adrenalin and noradrenalin levels were tested after electroacupuncture in points Baihui DU-20 and Zusanli ST36.Results The systolic and diastolic pressures were lower in the drug group and the electroacupuncture group than in the model group(P<0.05),and there was no difference between the 2 groups(P>0.05).The adrenalin and noradrenalin levels were higher in the model group than in the control group(P<0.05),but they were lower in the drug group and the electroacupuncture group than in the model group(P<0.05).Conclusion The electroacupuncture could reduce the blood pressure of acute hypertension rats by decreasing blood adrenalin and noradrenalin levels.