Cytogenetic analysis in 61 couples with spontaneous abortions |
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Authors: | JIANG Jing FU Manfen WANG Defen |
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Affiliation: | Department of Pediatrics, Ruijin Hospital, Shanghai Second Medical University, Shanghai 200025, China |
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Abstract: | Objective To examine the relationship between spontaneous abortion and chromosomal abnormalities Methods Couples who had one or more consecutive spontaneous abortions and had normal genitals were enrolled for cytogenetic karyotype analysis Results In the 61 couples, the detected incidence was 11 5%, with five Robertsonian translocations, one reciprocal translocation, and one pericentric inversion of chromosome 7 Conclusion Chromosomal abnormalities may play an important role in fetal wastage |
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Keywords: | spontaneous abortion chromosomal abnormality reciprocal translocation pericentric inversion |
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