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Cytogenetic analysis in 61 couples with spontaneous abortions
Authors:JIANG Jing  FU Manfen  WANG Defen
Affiliation:Department of Pediatrics, Ruijin Hospital, Shanghai Second Medical University, Shanghai 200025, China
Abstract:Objective To examine the relationship between spontaneous abortion and chromosomal abnormalities Methods Couples who had one or more consecutive spontaneous abortions and had normal genitals were enrolled for cytogenetic karyotype analysis Results In the 61 couples, the detected incidence was 11 5%, with five Robertsonian translocations, one reciprocal translocation, and one pericentric inversion of chromosome 7 Conclusion Chromosomal abnormalities may play an important role in fetal wastage
Keywords:spontaneous abortion  chromosomal abnormality   reciprocal translocation   pericentric inversion
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