HIV／AIDS患者并发贫血的临床分析

目的研究艾滋病患者（HIV／AIDS）并发贫血的情况，探讨贫血程度对判定HIV／AIDS患者病情进展的意义．方法对未经治疗的HIV／AIDS患者检测免疫功能指标（CD4＋T细胞）和全血细胞计数．遵循美国疾病控制与预防中心（CDC）1993年诊断标准，对86例HIV／AIDS患者按照CD4＋计数分为A、B、C组．对血红蛋白浓度（HGB）与CD4＋T细胞之间的关系进行统计学分析．结果86例HIV／AIDS患者中有32例并发贫血，在A、B、C组贫血的发生率分别为61．5％、21．8％、6．7％，贫血发生率在3组间差异有显著的统计学意义（P〈0．01）．32例贫血患者的HGB均值在3组间差异有显著的统计学意义（P〈0．01）．不同CD4＋分组中贫血形态分类差异无统计学意义．结论AIDS患者贫血的发生率较高，贫血的发生率及严重程度随着病情的进展而发展．HGB随着免疫功能的衰减而下降．贫血的程度对AIDS患者的病情评判有重要意义．

The Clinical Study of Anemia among HIV/AIDS Patients

Objective To comprehend the condition of anemia among HIV/AIDS patients and evaluate its role in assessing the progression of HIV/AIDS. Methods Eighty six HIV/AIDS patients were detected for the index of immunological function （CD4^＋ T cell） and the whole blood cell count and divided into three groups （A, B, C） according to the diagnostic standard of US Center of Disease Control and Prevention. The relationship between the hemoglobin （HGB） and CD4^＋ T was analyzed statistically. Results There were 32 cases of anemia in 86 HIV/AIDS patients. The incidence of anemia was 61.5% in group A, 21.8% in group B and 6.7% in group C. The incidence of anemia was significantly different among the three groups （P 〈 0.01 ） . The level of HGB in 32 cases of anemia was notably different among the three groups （P 〈 0.01 ）. There was no statistic significance of anemia status among different groups with CD4＋ count （ P 〉 0.05）. Conclusion The incidence and degree of anemia parallel with the progression of HIV/AIDS. HGB decreases with the descending of immunological function. The level of anemia plays an important role in assessing progression of HIV/AIDS.