70岁以上老年女性乳腺癌39例分析

目的分析70岁以上老年女性乳腺癌患者的临床、病理特点，生存率和影响预后的因素。方法收集我院1997-01～2007—12收治的39例70岁以上老年乳腺癌患者的临床资料，并对患者的生存情况和临床特点进行统计分析。结果39例老年乳腺癌占同期收治乳腺癌患者的28．26％。89．79％的患者以乳房肿块为首发症状，53．8％患者合并其他疾病。主要病理类型为浸润性导管癌（82．1％）。免疫组化分析显示，雌孕激素受体阳性者占66．9％。结论老年乳腺癌具有独特的临床和病理特点，手术和内分泌治疗是主要和有效的治疗方式。

Clinical analysis on breast cancer patients over 70 years of age

Objective To investigate the clinical characteristics and prognostic factors in breast cancer patients over 70 year of age. Methods From 1997 to 2007, 39 female breast cancer patients over 70 years old were treated and the data were retrospectively reviewed. The clinical features including age, comorbidity, initial symptom, approaches, and overall survival were analyzed. Results These 39 patients accounted for 28.26 % of all breast cancer patients registered in our institution during the same period. Presentation of breast lump as initial symptom accounted for 89.7% of the patients. 53.8% patients had comorbidity such as coronary heart disease, hypertention, diabetes, etc. Major pathological type was invasive ductal carcinoma （ 82.1% ） . Estrogen or progesterone receptor was found to be positive in 66.9 % by immunohistochemical staining. Conclusion Female breast cancer patients over 70 years of age exhibit distinctive clinical and pathological characteristics. Surgery and endocrine therapty are main and effective treatment methods.