副溶血弧菌耐药现状及耐药机制

副溶血弧菌是一种重要的食源性疾病致病菌，其引起的感染已成为严重的全球性公共卫生问题。水产养殖业和临床上抗生素使用不规范，会直接导致或加剧副溶血弧菌耐药。一方面，耐药菌可通过食物链进入人体，给临床治疗副溶血弧菌感染带来巨大挑战；另一方面，耐药菌中的可移动遗传元件可以将耐药基因传递给其他细菌，从而产生更大的威胁。本文主要概述了副溶血弧菌的耐药现状、耐药机制及相应的耐药检测方法，为副溶血弧菌耐药产生、传播及控制提供参考。

Characteristics and mechanisms of antibiotic resistance of Vibrio parahaemolyticus

Vibrio parahaemolyticus is an important foodborne pathogen. V. parahaemolyticus infections have become a severe global public health problem. As the abuse of antibiotics in aquaculture,animal husbandry and clinic,the pathogen's drug resistance has become a serious problem. Drug-resistant bacteria can infect human beings through food chain,which pose a great challenge to clinical treatment and threat to human health. This review focus on the characteristics,mechanisms and detections of antibiotic resistance of V. parahaemolyticus,which can provide references for other in-depth research about the produce and spread of antibiotic resistance.