苦参提取工艺优选

目的:优选苦参提取工艺参数。方法:以苦参总生物碱和干膏率为考察指标,单因素试验考察提取溶媒、溶媒pH;采用正交试验法,选取溶媒用量、提取时间、提取次数为考察因素,以苦参总碱总量和固含物总量的总权重为考察指标,优选苦参提取工艺。结果:优选的提取工艺为加0.2%盐酸溶液提取3次,每次加6倍量溶媒,每次提取2 h。结论:该优选工艺稳定可行,可用于苦参的工业化提取。

Optimization of Extraction Process for Sophora flavescens

Objective:To optimize extraction process parameters of Sophorae flavescens. Method: With total alkaloids from S. flavescens and dry extract as indexes,extraction solvent and pH of solvent were investigated by single factor test;With total weight of the content of total alkaloids and solid as indexes,Orthogonal design was used to investigate effect of solvent consumption,extraction time,extraction times on extraction process. Result: Optimal extraction process was:extracted 3 times with 6 times the amount of 0.2% hydrochloric acid,2 hours each time. Conclusion: This optimized technology was stable and feasible,it could be used to industrial extraction of S. flavescens.