新疆地区913例心脏瓣膜置换术的临床分析

目的 分析新疆地区心脏瓣膜置换术的临床疗效,探讨该地区心脏瓣膜置换术的围手术期处理方法 .方法 对1993年1月至2007年12月新疆医科大学第一附属医院收治的913例心脏瓣膜病患者(均在中度低温体外循环下进行瓣膜置换手术),回顾性分析该组病例临床特点、手术适应证及围手术期处理情况.结果 913例患者中,痊愈出院868例(95.1%),术后住院期间因各种并发症死亡45例(4.9%).不同年龄以及不同心功能分级患者术后死亡率差异有统计学意义;不同手术年限以及不同心胸比例患者术后死亡率差异无统计学意义.结论 在新疆地区,瓣膜置换术仍是治疗心脏瓣膜病变的有效手段,对于年龄较大、心功能Ⅲ～Ⅳ级患者,应加强围手术期处理,以减少手术并发症,提高手术疗效.

Retrospective analysis of 913 cases of heart valve replacement in Xinjiang area

Objective To explore the perioperative experience of heart valve replacement in Xinjiang area. Methods A total of 913 cases underwent heart valve replacement in moderate hypothermia under cardiopulmonary bypass surgery in Xinjiang area. The clinical characteristic, indications and treatments of the patients were analyzed retrospectively. Results Among all cases, the overall recovery was 868 (95.1% ) cases. And 45 (4.9%) patients died of postoperative complications. The mortality had significant differences between different age groups and different NYHA classification groups. And there was no significant difference between different operation time groups and different cardiothoracic ratio groups.Conclusion Valve replacement surgery is still an effective therapy for valvular diseases in Xinjiang area.Enhancing preoperative care for elders and patients with poor cardiac function can decrease the perioperative complications and mortality rate so as to improve the surgical efficacies.