| 抗心肌球蛋白抗体在风心病患儿血清中的变化 |
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| 引用本文： | 江杰,杨作成,旷寿金,陈淳嫒,黎敏,李红卫. 抗心肌球蛋白抗体在风心病患儿血清中的变化[J]. 中国现代医学杂志, 2003, 13(18): 34-35,38 |
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| 作者姓名： | 江杰 杨作成 旷寿金 陈淳嫒 黎敏 李红卫 |
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| 作者单位： | 中南大学湘雅三医院儿科,长沙,410013 |
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| 摘 要： | 目的 :为探讨儿童风湿性心脏病 (RHD)患者血清抗心肌球蛋白抗体 (ACMA)的变化及意义。方法 :采用酶联免疫吸附法 (ELISA)检测 2 7例RHD活动期、30例静止期患儿及 32例健康儿童的血清ACMA。结果 :活动期组阳性率 81.5 % (2 2 /2 7) ;静止期组及正常对照组阳性率分别为 16 .7% (5 /30 )和 3.1% (1/32 )。活动期组阳性率显著高于静止期组及正常对照组 (P <0 .0 1)。静止期组与正常对照组无显著差异 (0 .0 5
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| 关 键 词： | 抗心肌球蛋白抗体 风湿性心脏病 儿童 |
CHANGES OF SERUM ANTI-CARDIAC MYOSIN ANTIBODY IN CHILDREN WITH RHEUMATIC HEART DISEASE |
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| Jiang Jie,Yang Zuocheng,Kuang Shoujin,et al.. CHANGES OF SERUM ANTI-CARDIAC MYOSIN ANTIBODY IN CHILDREN WITH RHEUMATIC HEART DISEASE[J]. China Journal of Modern Medicine, 2003, 13(18): 34-35,38 |
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| Authors: | Jiang Jie Yang Zuocheng Kuang Shoujin et al. |
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| Affiliation: | Jiang Jie,Yang Zuocheng,Kuang Shoujin,et al. Department of Pediatrics,The Third Xiangya Hospital Central South University,Changsha 410013 |
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| Abstract: | Objective:In order to explore the changes and the significance of serum anti-cardiac myosin antibody (ACMA) in children with rheumatic heart disease(RHD). Methods:We measured the serum ACMA levels in 27 RHD subjects ,30 convalescent subjects and 32 healthy children as control with enzyme-link immunosorbent assay .Results:The positive rate of the acute stage group was 81.5%(22/27), while those of the convalescent group and the healthy control group were 16.7%(5/30) and 3.1%(1/32) respectively. The positive rate of acute stage group was significanfiy higher than that of the convalescent group and that of the healthy control group (P<0.01), while the positive rates between the convalescent group and the healthy control group had no significant difference (0.05
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| Keywords: | Anti-cardiac Myosin Antibody Rheumatic Heart Disease Children |
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