孢子丝菌病样皮肤淋巴管综合征

孢子丝菌病样皮肤淋巴管综合征因临床上易误诊为皮肤淋巴管型孢子丝菌病导致治疗失败而引人关注。该综合征可由某些真菌、细菌、分枝杆菌、寄生虫等病原体经皮肤直接外伤种植引起。特征性表现为向心性淋巴管引流区域分布的皮下结节和/或淋巴管炎。寻找相关的流行病学因素及合适的实验室检查确定病原体是确诊的关键。根据分离的病原体及相应的药敏试验结果确定最佳治疗方案。

Sporotrichoid Lymphocutaneous Syndrome

Sporotrichoid lymphocutaneous syndrome is often misdiagnosed as lymphocutaneous sporotrichosis and mis-treated. The syndrome may be caused by a number of fungal, bacteria, mycobacteria, and parasitic pathogens that be inoculated through cutaneous traumas. The typical features are subcutaneous nodules and/or lymphangitis along the centripetal lymphatic vessels draining the area. Confirmation of diagnosis depends on detailed epidemiologic history and proper laboratory tests to identify the causative pathogens. The results of identification of pathogens and antimicrobial susceptibilities are crucial for selecting appropriate antimicrobial therapy.