血糖与心肌梗死患病风险及结局的关系

目的探讨空腹血糖（FPG）水平与心肌梗死患病风险及结局的关系。方法参照代谢综合征与糖尿病诊断标准,将研究对象分为FPG正常（FPG〈6.0mmol/L）、FPG升高（FPG6.0-6.9mmol/L）和FPG异常（FPG≥7.0mmol/L）3组。以肢体瘫痪或死亡为不良结局。采用多中心协作的病例对照研究及多因素调整的Logistic回归方法对FPG水平与心肌梗死患病风险及结局关系进行了分析。结果心肌梗死患者的FPG水平[（7.22±3.45）mmol/L]高于对照组[（5.05±1.35）mmol/L],高血糖率（51.5%）高于对照组（10.9%）,差异均有高度统计学意义（均P〈0.01）。年龄增大和高血糖与心肌梗死不良结局有关联。运用Logistic回归分析方法,以FPG正常为参照,经多因素调整后发现,FPG升高和异常时糖尿病患病风险增高,OR值分别是6.625和10.457（P〈0.01）。以FPG正常为参照,FPG异常时出现不良结局的危险逐渐增加（OR=11.379,P〈0.01）。结论高血糖水平会增加心肌梗死及其不良结局的发生风险。

Risk Association Between Fasting Plasma Glucose and Myocardial Infarction and Its Outcome

Objective To explore fasting plasma glucose as a risk factor to myocardial infarction and its outcome. Methods Case control study and multiple Logistic regression were used to analyze the relationship between risk of myocardial infarction its outcome and fasting plasma glucose and its outcome. Accor-ding to criteria of metabolic syndrome and diabetes, participants were divided into three groups: the normal FPG group(FPG<6.0 mmol/L), raised FPG group(FPG 6.0 ~ 6.9 mmol/L) and abnor- mal FPG group(FPG 7.0 mmo...