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呼吸道感染痰培养的病原菌分布及其耐药分析
引用本文:陈友军,唐双阳,李乐.呼吸道感染痰培养的病原菌分布及其耐药分析[J].中国卫生检验杂志,2011(8).
作者姓名:陈友军  唐双阳  李乐
作者单位:湖南省衡阳市妇幼保健院;南华大学医学院;南华大学公共卫生学院;
摘    要:目的:了解呼吸道感染患者的痰培养病原菌分布及其耐药性,指导临床合理用药。方法:采集2009年1月-2010年12月疑似呼吸道感染的患者的痰标本进行细菌分离培养、鉴定和药敏试验,并分析其病原学分布及对抗生素的耐药性。结果:6744份痰标本分离病原菌2236株,其中革兰阴性(G-)菌1526株,占68%;革兰阳性(G+)菌177株,占8%;真菌534株,占24%。以铜绿假单胞菌、鲍曼不动菌、大肠埃希菌、金黄色葡萄球菌和肺炎克雷伯菌为主要细菌。G+球菌对万古霉素、米诺环素较为敏感,而G-杆菌对美洛培南和亚胺培南的敏感性较高。结论:常见细菌耐药性有上升趋势,且具有多重耐药性。在治疗感染性疾病时应进行病原学检查,依据药敏试验结果合理使用抗生素,以减少耐药菌株产生。

关 键 词:呼吸道感染  痰培养  病原菌  耐药性  

Distribution and drug resistance of pathogens cultivated from sputum in respiratory tract infections
CHEN You-jun,TANG Shuang-yang,LI Le.Distribution and drug resistance of pathogens cultivated from sputum in respiratory tract infections[J].Chinses Journal of Health Laboratory Technology,2011(8).
Authors:CHEN You-jun  TANG Shuang-yang  LI Le
Institution:CHEN You-jun1,TANG Shuang-yang2,LI Le3 (1.Heng Yang Women and Children Health Hospital,Hengyang 410001,China,2.Medical College of University of South China,Hengyang 421001,3.School of Public Health in University of South China,China)
Abstract:Objective:In order to conduct the clinical use of antibiotics rationally,distribution and drug resistance of pathogens cultivated from sputum in respiratory tract infections(RTIs) were analyzed.Methods:The pathogens cultivated from sputum of the RTIs patients from January 2009 to December 2010 were identified and obtained susceptibility testing.Then their Distribution and drug resistance were analyzed.Results:A total of 2236 strains were isolated from 6744 samples,of which Gram-positive(G+) bacteria account...
Keywords:Respiratory tract infection  Sputum cultivation  Pathogen  Drug resistance  
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