| 缺血性脑卒中的发生与血清叶酸、血小板聚集率、同型半胱氨酸和维生素B12的关系研究 |
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| 引用本文： | 王秀梅,郝钦芳,陈烨.缺血性脑卒中的发生与血清叶酸、血小板聚集率、同型半胱氨酸和维生素B12的关系研究[J].中国卫生检验杂志,2011(12):2907-2908. |
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| 作者姓名： | 王秀梅 郝钦芳 陈烨 |
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| 作者单位： | 武警总医院检验科; |
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| 摘 要： | 目的:探讨缺血性脑卒中患者血清叶酸(Folic Acid,FA)、血小板聚集率(Platelet Aggregation Rate,PAR)、同型半胱氨酸(Homocysteine,Hcy)和维生素B12(vitamin B12,VitB12)变化的原因及其关系。方法:选择缺血性脑卒中患者和健康对照组各60例,利用免疫法测其FA、PAR、Hcy和vitamin B12水平。结果:缺血性脑卒中患者体内FA水平偏低,PAR、VitB12和Hcy水平偏高,P<0.05;与缺血性脑卒中关系依次为FA>VitB12>PAR>Hcy,FA与PAR的相关关系r=0.006,P<0.01;HCY与PAR的相关关系r=0.03,P<0.05,FA与HCY的相关关系r=0.07。结论:缺血性脑卒中患者FA水平偏低,补充叶酸能降低PAR、改善HCY的氧化和VitB12的吸收,降低缺血性脑卒中的发生。
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| 关 键 词： | 叶酸 血小板聚集率 同型半胱氨酸 维生素B12 缺血性脑卒中 |
Research on relationship of the occurrence of ischemic stroke with serum folic acid,platelet aggregation rate,homocysteine and vitamin B_(12) |
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| WANG Xiu-mei,HAO Qin-fang,CHEN Ye.Research on relationship of the occurrence of ischemic stroke with serum folic acid,platelet aggregation rate,homocysteine and vitamin B_(12)[J].Chinses Journal of Health Laboratory Technology,2011(12):2907-2908. |
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| Authors: | WANG Xiu-mei HAO Qin-fang CHEN Ye |
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| Institution: | WANG Xiu-mei,HAO Qin-fang,CHEN Ye(Department of Clinical Laboratory,General Hospital of Armed Police Forces,Beijing 100039,China) |
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| Abstract: | Objective:To explore the reason of changes and the interrelationships of serum Folic Acid(FA),Homocysteine(Hcy),Platelet Aggregation Rate(PAR) and vitamin B12(VitB12) in ischaemic stroke patients.Methods: 60 ischemic stroke patients and 60 healthy controls were selected for concentration detection of FA,PAR,VitB12 and Hcy by immune method.Results: FA level is low in ischemic stroke patients,while PAR,VitB12 and Hcy level were high(P<0.05).The intimate degree to ischemic stroke is FA>VitB12>PAR>Hcy.The corre... |
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| Keywords: | Folic acid Platelet aggregation rate Homocysteine Vitamin B12 Ischemic stroke |
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