| 2009年-2010年义乌市手足口病病原监测结果分析 |
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| 引用本文： | 陈劲华,翁正军,陈步青,朱列波,陶静波.2009年-2010年义乌市手足口病病原监测结果分析[J].中国卫生检验杂志,2011(10). |
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| 作者姓名： | 陈劲华 翁正军 陈步青 朱列波 陶静波 |
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| 作者单位： | 浙江省义乌市疾病预防控制中心; |
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| 摘 要： | 目的:了解2009年-2010年浙江省义乌市手足口病(HFMD)的病原体型别及分布特征,为今后制定预防和控制HFMD防治策略提供依据。方法:采用实时荧光RT-PCR方法,对义乌市248例HFMD临床诊断病例标本进行EV、EV71和CoxA16RNA的检测。结果:共检出178例EV阳性病例,阳性率为71.77%;其中EV71阳性病例83例,CoxA16阳性病例66例,分别占EV阳性病例的46.63%、37.08%;5岁以下儿童EV感染占所有感染者的92.74%;2009年和2010年儿童EV71、CoxA16阳性率分别为17.86%、37.50%和38.05%、23.44%,结果差别有统计学意义;不同性别儿童EV、EV71和CoxA16阳性率差别无统计学意义;重症病例EV71阳性检出率为75.00%。结论:引起义乌市HFMD的主要病原体为EV71和CoxA16,其中2009年多数为CoxA16,其次为EV71,2010年多数为EV71、其次为CoxA16;5岁以下儿童是EV感染的高危人群;EV71是引起重症病例的主要病原体。
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| 关 键 词： | 手足口病 肠道病毒7l型 柯萨奇病毒A16型 |
Analysis of HFMD surveillance during 2009-2010 in Yiwu |
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| CHEN Jin-hua,WENG Zheng-jun,CHEN Bu-qing,ZHU Lie-bo,TAO Jing-bo.Analysis of HFMD surveillance during 2009-2010 in Yiwu[J].Chinses Journal of Health Laboratory Technology,2011(10). |
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| Authors: | CHEN Jin-hua WENG Zheng-jun CHEN Bu-qing ZHU Lie-bo TAO Jing-bo |
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| Institution: | CHEN Jin-hua,WENG Zheng-jun,CHEN Bu-qing,ZHU Lie-bo,TAO Jing-bo(Yiwu Center for Disease Control and Prevention,Yiwu 322000,China) |
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| Abstract: | Objective:To understand etiological classification and distribution features of HFMD,in order to provide the references for preventing and controlling the HFMD disease and the enterovirus.Methods: The RNA of enterovirus,enterovirus 71 and coxsackie virus A16 from 248 HFMD specimens confirmed by clinical measures were detected by using real time PCR.Results: The 178 specimens were positive to enterovirus,and the positive rate was 71.77%.Furthermore,in the above results,there were 83 cases positive to enterov... |
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| Keywords: | Hand-foot-mouth disease Enterovirus 71 Coxsackie virus A16 |
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