支气管肺泡灌洗液培养在肺部感染监测中的应用研究

目的:探讨支气管肺泡灌洗液(BALF)培养在肺部感染中的应用价值。方法:对152例肺部感染患者BALF培养结果进行病原菌种类及药敏分析。结果:培养阳性标本78例,阳性率51.3%,共分离出病原菌94株,其中革兰阳性球菌占11.7%,以金黄色葡萄球菌为主;革兰阴性杆菌占64.9%,以鲍曼不动杆菌为主,其次为铜绿假单胞菌;真菌占23.4%,以白色念珠菌为主。阳性球菌对万古霉素、替考拉丁最敏感;阴性杆菌对亚胺培南、美罗培南耐药率低;念珠菌对两性霉素B的敏感率高。结论:肺部感染患者行支气管肺泡灌洗液培养,对明确病原、指导抗生素的合理应用有重要临床意义。

Application of bronchoalveolar lavage fluid culture in investgation of patients with pulmonary infection

Objective:To investigate the curative effect of Bronchoalveolar Lavage fluid(BALF) in patients with pulmonary infection.Methods: The bacteria types in BALF samples and drug sensitivity test in 152 pulmonary infection cases were analyzed retrospectively.Results: There were 94 strains of pathogens isolated from 78 pulmonary infection cases,the positive rate of BALF culture was 51.3%,61 strains of Gram-negative bacilli were found in 94 strains of bacteria,accounting for 64.9%.The main Gram-negative bacilli wer...