超声检测类风湿关节炎膝关节滑膜改变及其血流的临床应用价值

目的：通过观察类风湿关节炎（rheumatoid arthritis ，RA ）膝关节滑膜病变的超声声像图表现，分析滑膜病变超声检查结果与RA活动度的相关性，探讨超声检查RA膝关节滑膜病变的临床应用价值。方法对38例RA患者患侧膝关节和20例正常对照者双侧膝关节行超声检查，根据DAS28评分结果将RA患者分组，分别对比各组与对照组的滑膜厚度，髌上囊积液；分析RA组超声检测结果与DAS28评分之间的相关性。结果 RA组滑膜厚度较对照组明显增厚，髌上囊积液明显增多（ P ＜0．05）。RA组膝关节滑膜厚度、关节积液及滑膜内血流信号分级与RA患者DAS28评分之间存在一定的相关性（ P ＜0．05）。结论超声检查对RA膝关节滑膜病变具有一定的的诊断价值，与DAS28评分的相关性较好，可以作为评估RA膝关节滑膜病变常规检查方法之一。

The clinical value of knee synovial changed and blood flow in rheumatoid arthritis detected by ultrasound

Objective By observing sonographic features of knee synovial lesions in rheumatoid arthritis （RA） and analy‐sing the correlation between sonographic result and clinical activity ,we explored the clinical value of ultrasound detection of synovial lesions in RA .Methods Ipsilateral knees of thierty‐eight RA patients and bilateral knees of twenty healthy a‐dults were detected by ultrasound .RA patients were grouped depending on DAS28 .Synovial thickness and the patellar bursa fluid of RA group were compared with the control group .The correlation between ultrasound results and DAS28 in patients with RA was observed .Results Synovial thickness of RA group was significantly thicker than that of control group and patellar bursa fluid increased significantly （ P〈0 .05） .In RA group ,there was certain correlation between ul‐trasound results ,including thickness of synovium ,joint effusion and classification of synovial blood test ,and DAS28 in patients with RA （ P 〈0 .05） .Conclusion Utrasound has diagnostic value on knee synovial lesions in RA and has good correlation with DAS28 .It can serve as a common method in assessing knee synovial lesions in RA .