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1.5mmol/L钙浓度透析液对血清总钙和全段甲状旁腺激素及血压的影响
引用本文:左力,王梅,张路霞.1.5mmol/L钙浓度透析液对血清总钙和全段甲状旁腺激素及血压的影响[J].临床内科杂志,2003,20(8):411-413.
作者姓名:左力  王梅  张路霞
作者单位:100034,北京大学第一医院肾脏内科
摘    要:目的 针对血液透析患者出现的高钙血症,观察将透析液钙浓度从1.75mmol/L(HCaD)降低到1.5mmol/L(LCaD)后对血清钙、磷、全段甲状旁腺激素(iPTH)和血压的影响。方法选择存在高钙血症、使用HCaD的稳定HD患者32例,改用LCaD透析3个月。记录LCaD治疗前后透析中症状、透析前后收缩肜舒张压和心率、血清总钙以及透析前全段甲状旁腺激素(iPTH)。结果 LCaD治疗3个月后收缩压趋于正常,高钙血症得到纠正,低iPTH患者血清iPTH水平升高,LCaD没有影响活性维生素D的疗效。结论 LCaD的使用有利于血液透析患者高钙血症的纠正和血压的控制。

关 键 词:血液透析  高钙血症  透析液钙浓度  全段甲状旁腺激素  血压
文章编号:1001-9057(2003)08-0411-03
修稿时间:2002年8月29日

Influence of 1.5mmol/L calcium dialysate on serum total calcium,iPTH and blood pressure
Zuo Li,Wang Mei,Zhang Luxia.Influence of 1.5mmol/L calcium dialysate on serum total calcium,iPTH and blood pressure[J].Journal of Clinical Internal Medicine,2003,20(8):411-413.
Authors:Zuo Li  Wang Mei  Zhang Luxia
Institution:Zuo Li,Wang Mei,Zhang Luxia.Institute of nephrology,First Hospital,Peking University,Beijing 100034,China
Abstract:Objectives To investigate the effects of decreasing dialysate calcium concentration from 1.75 mmol/L(HCaD)to 1.5 mmol/L(LCaD)on serum calcium,phosphate,iPTH and blood pressure during the treatment of hypercalcaemia in hemodialyzing patients.Methods Thirty two stable patients on HCaD dialysis who had hypercalcaemia were changed to LCaD for 3 months.The symptom,per and post dialysis blood pressure and heart rate,serum calcium,phosphate and iPTH were recorded.Results After LCaD dialysis for 3 months,systolic blood pressure and serum calcium concentration tended to become normal,iPTH level increased in patients with low iPTH level.Conclusion LCaD is beneficial to blood calcium concentration and systolic blood pressure control.
Keywords:Renal failure  Hemodialysis  Hypercalcaemia
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