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目的 探讨原发性甲状腺恶性淋巴瘤的诊断和治疗方法.方法 回顾性分析2000年1月至2006年4月中国医科大学附属第一医院普通外科收治的5例原发性甲状腺恶性淋巴瘤临床资料.结果 5例病人术前均诊断为甲状腺癌,1例行双侧甲状腺切除术,2例行患侧甲状腺及峡部切除术、对侧甲状腺大部切除和气管切开术,该3例病人术后给予化疗.2例因呼吸困难急诊手术,其中1例术后死亡.术后病理均证实为甲状腺恶性B细胞非何杰金淋巴瘤.结论 原发性甲状腺淋巴瘤诊断较困难,治疗应采用综合治疗.

Clinical analysis of 5 cases primary thyroid lymphoma

??Objective:To analyze the diagnosis and therapy of primary thyroid malignant lymphoma. Methods:5 cases of primary malignant thyroid lymphoma admitted in the Department of General Surgery in the First Affiliated Hospital of China Medical University between January 2000 and April 2006 were reviewed. Results:Thyroid carcinoma was diagnosed for 5 cases before operation, bilateral thyroidectomy was undergone in 1 case,thyroid and isthmus resection with the involved side and the other side partial thyroidectomy and tracheotomy were done in 2 cases,chemotherapy was undertaken in the above 3 cases after operation.Emergency operation was done because of dyspnoea in 2 cases,postoperative death occurred in 1 case.Postoperative histologic findings were B??cell original Non??Hodgkin’s thyroid malignant lymphoma in all cases. Conclusion:The right diagnosis is difficult in primary malignant thyroid lymphoma,the patients should be treated with multidisciplinary combined therapy.