| 变应性真菌性鼻-鼻窦炎的综合诊断 |
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| 引用本文： | 王向东,王成硕,宋晓红,伯铭羽,李颖,王鸿,张罗.变应性真菌性鼻-鼻窦炎的综合诊断[J].首都医学院学报,2012,33(6):735-739. |
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| 作者姓名： | 王向东 王成硕 宋晓红 伯铭羽 李颖 王鸿 张罗 |
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| 作者单位： | 首都医科大学附属北京同仁医院耳鼻咽喉头颈外科 北京市耳鼻咽喉科研究所 耳鼻咽喉头颈科学教育部重点实验室, 北京 100730 |
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| 基金项目： | 国家杰出青年科学基金(30872846);北京市卫生局系统层次人才项目(2011-3-039);北京市人力资源和社会保障局留学归国人员择优资助项目~~ |
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| 摘 要： | 目的评价变应性真菌性鼻-鼻窦炎诊断方法的临床应用。方法总结18例变应性真菌性鼻-鼻窦炎病例,分析其临床特点、CT和MRI影像学特征,通过皮肤点刺试验、血清学检查结果、鼻窦分泌物压片/涂片和培养确定致病真菌的种类,通过病理学方法观察黏膜组织和变应性黏蛋白的特点。结果 18例患者中,男性11例,女性7例,患者年龄17～66岁,通过皮肤点刺试验、血清特异性IgE检测结合真菌压片/涂片和培养检查,明确致病真菌主要为曲霉菌,黏蛋白病理学检查可见嗜酸性粒细胞和Charcot-Leyden晶体。结论变应性真菌性鼻-鼻窦炎的诊断需要综合临床表现、影像学特点、皮肤点刺试验和血清学检查、真菌病原学以及病理学检查。
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| 关 键 词： | 真菌 变态反应 诊断 皮肤试验 |
| 收稿时间： | 2012-09-20 |
Combined diagnosis of allergic fungal rhinosinusitis |
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| WANG Xiangdong,WANG Chengshuo,SONG Xiaohong,BO Mingyu,LI Ying,WANG Hong,ZHANG Luo.Combined diagnosis of allergic fungal rhinosinusitis[J].Journal of Capital University of Medical Sciences,2012,33(6):735-739. |
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| Authors: | WANG Xiangdong WANG Chengshuo SONG Xiaohong BO Mingyu LI Ying WANG Hong ZHANG Luo |
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| Institution: | Department of Otorhinolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing Institute of Otorhinolaryngology, Key Laboratory of Otorhinolaryngology Head and Neck Surgery, Ministry of Education, Beijing 100730, China |
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| Abstract: | Objective To evaluate the clinical application of different diagnostic methods in the diagnosis of allergic fungal rhinosinusitis. Methods Eighteen cases of allergic fungal rhinosinusitis were enrolled in the present study, clinical characteristics, CT and MRI images, skin prick tests(SPTs), serum specific IgE, smear and culture of mucin and pathological diagnosis were used as diagnostic methods. Results The ratio of male to female was 11/7, and the age range was 17~66 years. The CT and MRI of sinuses showed typical characteristics. The main fungus was aspergillus diagnosed by SPTs, serum specific IgE, smear and culture of mucin in sinuses. Eosinophils and Charcot-Leyden crystals could be found in mucin. Conclusion The diagnosis of allergic fungal rhinosinusitis depends on combination of clinical characteristics, CT and MRI images, SPTs, serum specific IgE, smear and culture of mucin and pathological diagnosis. |
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| Keywords: | fungus allergy diagnosis skin prick tests |
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