监测细菌耐药率 合理应用抗菌药物

目的分析我院住院患者抗菌药物的使用情况,监测细菌对抗菌药物的耐药率,为合理应用抗菌药物提供依据。方法采用回顾性调查的方法对出院病历13 990份进行统计分析。结果我院住院患者使用抗菌药物注射剂28个品种,抗菌药物的使用率76.15%,三联用药率仅占0.44%。结论我院住院患者应用的抗菌药物较多,同时有部分抗菌药物产生高度耐药性。应重新调整《总医院抗菌药物分级管理细则》,适当控制头孢曲松钠、克林霉素、阿齐霉素的用量。同时,应根据细菌感染情况适当选用头孢呋辛钠,以进一步提高抗菌药物合理应用水平。

To use the antimicrobial agents reasonably by monitoring the bacterial resistance

Objective To analyze the use of antibacterial drugs,monitor the bacterial antimicrobial resistance rates,and provide a reasonable basis for the use of antimicrobial agents.Methods A retrospective survey was used for the analysis of 13 990 cases.Results There were 28 types of antimicrobial agents injection,and the use rate of antibacterial drug was 76.15%.The drug use of majority of cases was single or double use,triple use was only 0.44%.Conclusion The antibiotics used by the inpatients of our hospital is much more,and some antibiotics has high resistance.The use of ceftriaxone,clindamycin,aceh should be controlled properly.The cefuroxime sodium should be chose appropriately on the basis of bacterial infection,and the level of the rational use of antimicrobial agents could be raised.