抗脂肪肝冲剂对大鼠乙醇性肝损伤防治的实验研究

目的：探讨抗脂肪肝冲剂对乙醇性肝损伤大鼠脂质代谢的影响,寻找针对乙醇所致脂肪肝的有效药物,方法：采用乙醇慢性肝损伤模型,观察大鼠肝组织总胆固醇（TC）,及甘油三酯（TG）的含量,结果：抗脂肪肝冲剂降低乙醇性肝损伤大鼠肝组织TC,TG的含量,与模型组比较P＜0．05（小剂量组）,P＜0．01（中,大剂量组）,病理检查,抗脂肪冲剂各剂量组与模型组比较P＜0．01,结论：抗脂肪肝冲剂能够降低乙醇性肝损伤大鼠肝组织TG,TC的含量,具有防治乙醇性脂肪肝的作用。

Effect of Anti-fatty Iiver Granule on Preventing and Treating Hepatic Damage by Ethanol in Mice

To explore the effect of the "Anti-Fatty Liver Granule" on the hepatic fat metabolism of the mice which were damaged by ethanol. To find a effective medicine for "fatty liver"mediated by ethanol. Methods: Using the models which were damaged chronically by ethanol, the mice's hepatic content of TG and TC were investigated. Result: The hepatic content of TC and TG in these mice were declined by the "Anti-Fatty Liver Granule". Compared with the models: P<0. 05 (small dosage), P<0. 01 (middle and large dosage), with the pathology checking, P<0. 01 on every group of "the dosage". Conclusion: The "Anti-Fatty Liver Granule" can decline the content of TC and TG in the hepatic damaged mice mediated by ethanol. It have the function of treating and preventing the "fatty liver".