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| 复方虫草多糖含片质量控制方法的研究 | |
| 引用本文： | 苏颖,宋艳,黄蕾,邹豪,周选围. 复方虫草多糖含片质量控制方法的研究[J]. 药学实践杂志, 2008, 26(3): 191-193,221 |
| 作者姓名： | 苏颖 宋艳 黄蕾 邹豪 周选围 |
| 作者单位： | 1. 上海交通大学农业与生物学院,上海,200030 2. 黑龙江新医圣制药有限责任公司,黑龙江鸡东县,158200 3. 第二军医大学药学院,上海,200433 |
| 基金项目： | 上海交通大学本科生PRP研究计划项目 |
| 摘 要： | 目的:制定复方虫草多糖含片(北冬虫夏草多糖提取物,罗汉果提取物,西洋参提取物,茶多酚)的质量控制方法.方法:对罗汉果,西洋参进行薄层鉴别;茶多酚进行显色鉴别;采用苯酚一硫酸法测定复方虫草多糖含片中虫草多糖的含量.结果:通过方法学考察,虫草多糖浓度范围内线性关系良好,相关系数0.9964;平均回收率为97.13%RSD=1.41%(n=5).结论:方法简便、准确、重现性高,可用于控制复方虫草含片的质量. |
| 关 键 词： | 虫草多糖 罗汉果提取物 西洋参提取物 茶多酚 质量控制 复方 虫草多糖 含片 质量控制方法 研究 tablets polysaccharide compound control 平均回收率 相关系数 线性关系 浓度范围 考察 方法学 结果 含量 测定 苯酚一硫酸法 薄层鉴别 |
| 文章编号： | 1006-0111(2008)03-0191-04 |
| 收稿时间： | 2008-03-31 |
| 修稿时间： | 2007-07-03 |
Quality control for compound cordycepic polysaccharide buccal tablets |
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| Su Ying,Song Yan,Huang Lei,Zou Hao and Zhou Xuan-wei. Quality control for compound cordycepic polysaccharide buccal tablets[J]. The Journal of Pharmaceutical Practice, 2008, 26(3): 191-193,221 | |
| Authors: | Su Ying Song Yan Huang Lei Zou Hao Zhou Xuan-wei |
| Affiliation: | Department of Food Technology and Science,Shanghai Jiao Tong University,Shanghai 200030,China;Heilongjiang Xingyisheng Sheng Pharmaceutical Co.,Ltd,Jidong 158200,China;Department of Food Technology and Science,Shanghai Jiao Tong University,Shanghai 200030,China;College of Pharmacy,Second Military Medical University,Shanghai 200433,China;Department of Food Technology and Science,Shanghai Jiao Tong University,Shanghai 200030,China |
| Abstract: | Objective:To establish a quality control method for compound cordycepic polysaccharide buccal tablets(cordycepic polysaccharide,extract of Grosvenor momordica fruit,Panax quinquefolium extract,and tea polyphenols).Methods:The extract of Grosvenor momordica and Panax quinquefolium L.were identified by TLC.Tea polyphenols was identified according to the principle of display reaction between tea catechins and vanillin.Cordycepic polysaccharide was determined by spectrophotometry method.Results:The methodological study showed that the calibration curve of polysaccharide was linear in the concentration range(r=0.996 4).The average recovery was 97.13% with the RSD of 1.41%(n=5).Conclusion:The method is simplea,ccurate,repeatilde with and high precision.This method can be used for quality control for compound cordycepic polysaccharide buccal tablets. |
| Keywords: | cordycepic polysaccharide,extract of Grosvenor momordica fruit,Panax quinquefolium extract tea polyphenols,quality control. |
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