| 冠心病患者血清脂蛋白（a）水平的测定及其临床意义 |
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| 引用本文： | 梁湘辉 黄彩芝. 冠心病患者血清脂蛋白（a）水平的测定及其临床意义[J]. 湖南医科大学学报, 2001, 26(3): 227-228 |
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| 作者姓名： | 梁湘辉 黄彩芝 |
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| 作者单位： | [1]中南大学湘雅医院检验科，长沙410008 [2]湖南省儿童医院检验科，长沙410007 |
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| 摘 要： | 目的：探讨血清脂蛋白(a)[Lp(a)]水平与冠心病（CHD）的关系。方法：CHD组患者39例，健康人对照组（CG）52例，分别检测血清Lp(a)、总胆固醇（TC）、高密度脂蛋白胆固醇（HDL－C）、甘油三酯（TG）、载脂蛋白AI（apoAI)、载脂蛋白B（apoB)，对检测结果进行统计学分析。结果：CHD组Lp(a)水平明显高于正常人对照（P＜0．01）;Lp(a)与TC，HCL－C，TG，apoAI,apoB均无明显相关性（P＞0．05）。结论：Lp(a)与CHD的发病密切相关，检测Lp(a)含量对临床预测和诊断CHD具有重要价值。
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| 关 键 词： | 脂蛋白（a） 血清诊断 冠心病 |
Detection of serum Lp(a) level of coronary heart disease and its clinical significance] |
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| X H Liang,C Z Huang. Detection of serum Lp(a) level of coronary heart disease and its clinical significance][J]. Bulletin of Hunan Medical University, 2001, 26(3): 227-228 |
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| Authors: | X H Liang C Z Huang |
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| Affiliation: | Department of Clinical Laboratory, Xiangya Hospital, Central South University, Changsha 410008, China. |
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| Abstract: | OBJECTIVE: To study the association of human serum Lp(a) level and coronary heart diseases. METHODS: Objects examined were conposed of 2 groups: CHD (39 cases) and healthy controls (52 cases). Lp (a), TC, HDL-C, TG, apoB of two groups were determined and the results were done with statistic analysis. RESULTS: The mean serum Lp(a) concentrations (mg.L-1) in coronary heart disease group were shown higher significantly than that in the control group (P < 0.01). However, there were no significant correlation between the mean serum Lp(a) and the mean serum TC, HDL-C, TG, spoAI and aopB.(P > 0.05). CONCLUSIONS: Serum Lp(a) level is closely related to the occurrence of coronary heart disease. Lp(a) is a single risk factor for coronary heart disease. Detecting the determination of serum Lp(a) is extremely valuable to the clinical prediction and diagnosis of CHD. |
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