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| 鼻腔无色素性恶性黑色素瘤的病理特征及鉴别诊断 | |
| 引用本文： | 王彩霞,王燕霞,王晓,王本才. 鼻腔无色素性恶性黑色素瘤的病理特征及鉴别诊断[J]. 黑龙江医药科学, 2003, 26(4): 29-31 |
| 作者姓名： | 王彩霞 王燕霞 王晓 王本才 |
| 作者单位： | 1. 佳木斯大学附属第一医院病理科,黑龙江,佳木斯,154002 2. 大连市中心医院病理科,辽宁,大连,116033 3. 佳木斯大学附属第二医院病理科,黑龙江,佳木斯,154002 |
| 摘 要： | 目的：探讨鼻腔原发性无色素性恶性黑色素瘤的病理特点及其鉴别诊断。方法：对9例鼻腔无色素恶性黑色素瘤进行光镜观察，并对全部病例作免疫组化染色。结果：光镜形态以细胞形态的多形性和组织结构的多样性为主要特点，免疫组化染色S-l00蛋白、HMB45及波形蛋白的阳性率分别为100％、88．9％和77．8％。结论：鼻腔无色素性恶性黑色素瘤组织学结构的变化特点有重要意义，免疫组织化学对其诊断及与鼻腔发生的其他肿瘤的鉴别诊断有重要价值。 |
| 关 键 词： | 鼻腔 黑色素瘤 黑色素瘤病理学 免疫组织化学 |
| 文章编号： | 1008-0104(2003)04-0029-03 |
| 修稿时间： | 2003-05-26 |
Pathological features and differential diagnosis of amelanotic malignant melanoma in nasal cavity |
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| WANG Cai-xia ,WANG Yan-xia ,WANG Xiao ,WANG Ben-cai. Pathological features and differential diagnosis of amelanotic malignant melanoma in nasal cavity[J]. Heilongjiang Medicine and Pharmacy, 2003, 26(4): 29-31 | |
| Authors: | WANG Cai-xia WANG Yan-xia WANG Xiao WANG Ben-cai |
| Affiliation: | WANG Cai-xia 1,WANG Yan-xia 2,WANG Xiao 1,WANG Ben-cai 3 |
| Abstract: | Objective: To study the pathological characteristics of primary nasal cavity amelanotic malignant melanoma (PNCMMM) and its differential diagnosis. Methods: 9 cases of PNCMMM were investigated at the light microscopic level ,and all case were studied by immunohistochemical techniques. Results: The principal features were the variety of cellular patterns and histologic structures. Immunohistochemically, the positive rates of the expression of S-100 protein, HMB 45 and vimentin in 9 case of PNCMMM were100%, 88.9%and77.8%, respectively. Conclusions: The histo-pathological features of PNCMMM are of great significance,and immunohistochemical staining plays an important role in its diagnosis and differential diagnosis of other tumors of the nasal cavity. |
| Keywords: | nasal cavity melanoma melanoma pathology immunohistochemically |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |