Expression of hepatocyte growth factor(hgf) and C-met gene in human gastric-cancer cell-lines |
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Authors: | Fushida S Yonemura Y Urano T Yamaguchi A Miyazaki I Nakamura T Shiku H |
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Affiliation: | UNIV WITWATERSRAND,SCH MED,DEPT MED,DIV CLIN HAEMATOL & MED ONCOL,YORK RD,JOHANNESBURG 2193,SOUTH AFRICA. JOHANNESBURG HOSP,JOHANNESBURG 2193,SOUTH AFRICA. |
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Abstract: | Tissue P-glycoprotein immunostaining was performed in seventy one patients with follicular large, mixed, or small cell non-Hodgkin's lymphomas. Only six patients (8.5%) demonstrated positive immunostaining for P-glycoprotein. All patients had complete and durable responses to initial therapy. P-glycoprotein (MDR) fails to predict for primary drug resistance in follicular lymphomas and is constitutionally expressed in only a few follicular lymphomas at present. |
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