涎腺膜性基底细胞腺瘤的临床病理研究

目的 探讨涎腺膜性基底细胞瘤的临床病理特点及生物学行为。方法 对１２例患者进行临床病理分析。结果 肿瘤由大小及形态不一的上皮团块所组成，团块外周细胞呈栅栏状排列，由玻璃样变的基底膜样物质围绕。４例伴头皮皮肤圆柱瘤，８例为多灶性肿瘤，１例恶变伴颈淋巴结转移。结论 诊断时应注意与实性型基底细胞腺瘤、基底细胞腺癌、实性型腺样囊性癌以及基底样鳞状细胞癌相鉴别。治疗应作全腮腺切除，并严密随访。

A clinicopathologic study on membranous basal cell adenoma

Objective To investigate the clinicopathologic feactures and behaviour of membranous basal cell ademoma.Methods Twelve cases with membranous basal cell adenoma of salivary gland were analysed clinicopathologically. Results The tumors were composed of epithelial islands of various sizes and shapes. Its histologic finding was characterized by palisading of peripheral cells and excessive hyaline basal membrane. Four cases had co existing dermal cylindromas of the scalp. In 8 cases, the tumors demonstrated multiple origin. One case showed malignant transformation and cervical lymph node metastasis. Conclusions The differential diagnosis involved the solid variant of basal cell adenoma, basal cell adenocarcinoma, solid subtype of adenoid cystic carcinoma and basaloid squamous cell carcinoma. Total parotidectomy rather than superficial parotidectomy is suggested to avoid the recurrence of the tumor. A close follow up after treatment is necessary.