头孢吡肟和头孢他啶治疗肺炎的成本-效果分析

目的 :比较头孢吡肟和头孢他啶治疗中、重度肺炎的疗效及费用。方法 :中、重度肺炎病人随机分为 2组 ,2 8例 (男性 2 6例 ,女性 2例 ;年龄 79a±s 6a)予头孢吡肟 1.0 g ,iv ,gtt ,bid。 2 8例 (男性 2 5例 ,女性 3例 ;年龄 78a± 4a)予头孢他啶 1.0 g ,iv ,gtt,q 8h。 2组均以 7～ 10d为一个疗程。结果 :2组临床有效率分别为 96 %和 93% (P >0 .0 5)。总医疗费用头孢他啶组较头孢吡肟组高 ,分别为 6 92 4元± 70 2元和 550 4元± 6 15元。结论 :2组疗效相同 ,费用有显著差异 ,头孢他啶组总医疗费用高。

Cost-effectiveness analysis of cefepime vs ceftazidime in treatment of pneumonia

AIM: To compare the efficacy and cost of cefepime vs ceftazidime in treating moderate severe pneumonia. METHODS: Fifty six patients were randomly divided into 2 groups. Twenty eight patients (M 26, F 2; age 79 a± s 6 a) were treated with cefepime 1.0 g iv, gtt, bid, for 7-10 d. Another twenty eight patients (M 25,F 3;age 78 a±4 a) were treated with ceftazidime 1.0 g iv, gtt, tid, for 7-10 d. RESULTS: The clinical effective rates of cefepime and ceftazidime were similar, 96% vs 93% respectively ( P >0.05), but the cost for ceftazidime was higher than that for cefepime 6924 Yuan±702 Yuan vs 5504 Yuan±615 Yuan, ( P <0.05). CONCLUSION: The ceftazidime has similar effect to cefepime, but its cost is higher.