组织工程化血管与种子细胞

摘要：血管组织工程学的目的就是在体外构建理想的血管移植物，植入体内后无免疫排异反应，能维持移植血管腔的长期通畅。临床上需要各种口径大小的血管作为手术修补材料或者其他自体或者异体甚至组织工程组织的滋养血管。文章采用了文献搜集和分析的方法，综述了血管组织工程的定义、自体血管壁细胞、胚胎干细胞、间充质干细胞、内皮祖细胞和平滑肌祖细胞的选择及其在应用中的优缺点。

Tissue-engineered blood vessels and seed cells

Abstract: Vascular tissue engineering is a novel approach by which an ideal vascular graft was constructed in vitro that will not be obstructed for a long time without immunological reaction after implantation. Vessel with various diameters is needed as repair material, autograft or allograft, even nutrient vessel for engineering tissues in clinic. The methods of documents collection, summary, and analysis are adopted in this paper, reviews the definition of vascular tissue engineering, the selection of embryonic stem cells, mesenchymal stem cells, endothelial progenitor cells, as well as smooth muscle progenitor cells, and the merits and demerits of each materials.