脑室出血量对幕上自发性脑出血患者预后的影响

目的研究脑室出血（IVH）对幕上自发性脑出血（ICH）患者预后的影响。方法前瞻性收集幕上自发性ICH合并IVH患者105例,运用IVH评分系统量化IVH体积,采用多因素Logistic回归分析消除混杂因素的影响。结果发病后30 d,根据改良Rankin量表（mRS）评估患者预后,本组预后较好45例（42.9%;mRS 0-2分）,预后较差60例（57.1%;mRS 3-6分）。预后较差患者IVH体积（26.5±14.1）ml]明显大于预后较好的患者（5.1±5.3）ml;P〈0.01]。多因素Logistic回归分析显示,IVH体积是ICH患者预后不良的独立危险因素（OR=2.17;95%置信区间为1.39-3.92;P〈0.05）。结论IVH体积是幕上自发性ICH患者预后不良的独立危险因素;合并IVH体积越大,患者预后越差。

Association between intraventricular hemorrhage volume and outcomes of patients with spontaneous supratentorial intracerebral hemorrhage

ObjectiveTo explore the effect of intraventricular hemorrhage（IVH）volume on the outcomes of patients with concomitant spontaneous supratentorial intracerebral hemorrhage（SSICH）and IVH.MethodsOne hundred and five patients with concomitant SSICH and IVH were prospectively recruited from August 2008 from December 2012 in this study.The IVH score was used to determine the IVH volume.The outcomes were assessed using 30-day modified Rankin scale（mRS）score.Multivariate logistic regression was used to adjust for potential confounders.ResultsThe IVH score ranged from 3 points to 20 points（mean,11.5±5.7 points）and the IVH volume ranged from 1.8 ml to 54.6 ml（mean,17.3±15.4 ml）.Of 105 patients with concomitant SSICH and IVH,45 had good outcomes（mRS 0-2）and 60 had poor outcomes（mRS 3-6）.The IVH volume was significantly larger in patients with poor outcomes（26.5±14.1 ml）than that（5.1±5.3 ml）in patients with good outcomes（P〈0.01）.In the multivariate logistic regression analysis,the IVH volume was an independent predictor of poor outcomes（OR=2.17;95% confidence interval：1.39-3.92;P〈0.05）.ConclusionThe IVH volume is an independent predictor of poor outcomes for patients with concomitant SSICH and IVH.