Atypical reactive ovarian surface epithelium, a pitfall in pathologic assessment

Abstract.   Aydin NE, Çelik Ö, Hasçalik Ş, Edali MN. Atypical reactive ovarian surface epithelium, a pitfall in pathologic assessment. Int J Gynecol Cancer 2006; 16(Suppl. 1): 207–210.
A 21-year-old parous woman was operated on due to a torsioned huge hemorrhagic benign ovarian mass. A wedge biopsy of the contralateral ovary revealed endophytic superficial cell clusters with atypical features raising suspicion of malignancy. Detailed pathologic and clinical workup proved these foci as reactive ovarian surface epithelium contrary to various initial interpretations as metastatic, deciduoid, or histiocytic by expert pathologists.