肺表面活性物质联合鼻塞持续气道正压通气在胎粪吸入综合征中的应用及护理

目的]探讨肺表面活性物质（PS）联合鼻塞持续气道正压通气（NCPAP）治疗胎粪吸入综合征（MAS）的应用方法及护理对策。方法]将我科41例重症MAS的患儿随机分为观察组和对照组,对照组患儿入院后即予NCPAP吸氧及常规治疗,观察组在对照组的基础上另给予PS（珂立苏）,按70mg/kg经气管内给药。结果]用药后观察组患儿的各项指标与治疗前比较,氧分压（PaO2）明显升高,二氧化碳分压（PaCO2）、所需氧浓度（FiO2）明显降低,患儿呼吸功能明显改善（均P〈0.05）;治疗后观察组患儿与对照组比较,上机时间、用氧时间、住院时间均缩短,差异有统计学意义（P〈0.05）。结论]PS与NCPAP联合应用能有效治疗MAS。

Application of pulmonary surfactant combined with nasal continuous positive airway pressure ventilation in meconium aspiration syndrome and nursing care of it

Objective： To probe into application of pulmonary surfactant combined with nasal continuous positive airway pressure ventilation in meconium aspiration syndrome and nursing countermeasures. Methods： My families and A total of 41 cases of severe MAS infants were randomly divided into observation group and control group, the control group patients were given NCPAP oxygen and conventional treatment after ad- mission,expect that the observation group patients were given PS,intratracheal administration with 70 mg/kg. Results： compared with before treatment,the indicators of observation group patients after medication were,partial pressure of oxygen （PaO2） was significantly higher, partial pressure of carbon dioxide （PaCO2）, oxygen concentration （FiO2） required significantly lower, respiratory function of ill children was improved significantly （all P〈0. 05） ;after treatment,computer time time of oxygen usage and the length of stay of observation group were shortened, the difference was statistically significant （P〈 0.05）. Conclusion： Pulmonary surfactant combined with nasal continuous positive airway pressure ventilation application can effectively treat infants with MAS.