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子宫血管周上皮样细胞肿瘤4例临床及病理分析
引用本文:李丹,常筱颖,杨向红,高霭峰. 子宫血管周上皮样细胞肿瘤4例临床及病理分析[J]. 现代肿瘤医学, 2010, 18(4). DOI: 10.3969/j.issn.1672-4992.2010.04.55
作者姓名:李丹  常筱颖  杨向红  高霭峰
作者单位:中国医科大学附属盛京医院病理科,辽宁,沈阳,110004
摘    要:目的:探讨子宫血管周上皮样细胞肿瘤的临床病理特征、免疫表型特征及鉴别诊断.方法:应用HE和免疫组化对4例PEComa进行观察并复习相关文献. 结果:胞浆透明或嗜酸的瘤细胞为梭形、上皮样,呈巢状、腺泡状排列,其间见丰富的薄壁血管.HMB45 SMA 均阳性表达.结论:子宫PEComa是一种较少见的间叶性肿瘤,易误诊为子宫平滑肌瘤,特征性的联合表达HMB45 SMA.子宫PEComa目前尚无确切的恶性诊断标准,属于恶性潜能未定的肿瘤.

关 键 词:血管周上皮样细胞肿瘤  子宫  平滑肌瘤

PEComa:a clinicopathological study of 4 cases
LI Dan,CHANG Xiao-ying,YANG Xiang-hong,GAO Ai-feng. PEComa:a clinicopathological study of 4 cases[J]. Journal of Modern Oncology, 2010, 18(4). DOI: 10.3969/j.issn.1672-4992.2010.04.55
Authors:LI Dan  CHANG Xiao-ying  YANG Xiang-hong  GAO Ai-feng
Affiliation:LI Dan,CHANG Xiao-ying,YANG Xiang-hong,GAO Ai-feng Department of Pathology,the Affiliated Shengjing Hospital of Chinese Medical University,Shenyang 110004,China.
Abstract:Objective:To investigate the clinicopathological and immunophenotypic features of uterine PEComa,Methods:Four cases of PEComa were investigated by light microscopy and the related literature was reviewed.Results:Diffuse,nested and /or fascicular proliferation of spindled and epithelioid cells that display clear to eosinophilic cytoplasms,and which display a perivascular distribution and immunoreactivity for HMB45 and SMA.Conclusion:PEComas of uterus is rare and to be easily misdiagnosed as uterine smooth mu...
Keywords:perivascular epithelioid cell tumor  uterus  smooth muscle tumor  
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