甲硝唑联合林可霉素与庆大霉素联合地塞米松治疗上颌窦炎的比较

目的 :比较甲硝唑联合林可霉素与庆大霉素联合地塞米松上颌窦注入治疗慢性化脓性上颌窦炎的疗效。方法 :慢性化脓性上颌窦炎 10 8例 (16 7侧 ) ,随机分为 2组。治疗组 5 7例 (92侧 )中男性 2 6例 ,女性 31例 ,年龄 2 6a±s11a ,用氯化钠注射液及 0 .5 %甲硝唑反复清洗 ,最后林可霉素 0 .6 g经上颌窦穿刺注入 ,5～ 7d 1次 ,3次为一个疗程。对照组 5 1例 (75侧 )中男性 2 3例 ,女性 2 8例 ,年龄 2 6a± 9a ,用庆大霉素 80mg ,地塞米松 5mg作上颌窦穿刺注入 ,疗程同上。结果 :治疗组总有效率 98% ,对照组为 88% (P <0 .0 1)。结论 :甲硝唑联合林可霉素作上颌窦穿刺注入治疗慢性化脓性上颌窦炎优于庆大霉素联合地塞米松

Comparison of effect of metronidazole combined with lincomycin and gentamycin combined with dexamethasone in treatment of chronic maxillary sinusitis

AIM:To compare the effect of metronidazole combined with lincomycin and gentamycin combined with dexamethasone in the treatment of chronic maxillary sinusitis. METHODS:One hundred and eight patients of chronic maxillary sinusitis were randomly seperated into two groups. Fifty seven patients (92 sides),(M 26, F 31; age 26 a± s 11 a) in the treatment group were treated with 0.5 % metronidazol and sodium chlorlde injection to wash the maxillary sinus repeatedly; then lincomycin 0.6 g was punctured into it.Fifty one patients (75 sides) (M 23, F 28; age 26 a±9 a) in the control group were treated with gentamycin 80 mg and dexamethasone 5 mg. Both courses were same. One course contained three times, once 5 7 d. RESULTS:The total effective rate of the treatment group was 98 % the control group was 88 % ( P < 0.01 ). CONCLUSION:Metronidazole combined with lincomycin is superior to gentamycin combined with dexamethasone in the treatment of chronic maxillary sinusitis.