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The efficacy of apparent diffusion coefficient value calculation in differentiation between malignant and benign thyroid nodules
Authors:Dilli Alper  Ayaz Umit Yasar  Cakir Evrim  Cakal Erman  Gultekin Salih Sinan  Hekimoglu Baki
Institution:1. Department of Radiology, D??kap? Y?ld?r?m Beyaz?t Training and Research Hospital, Ministry of Health, Ankara, Turkey;2. Department of Radiology, Mersin Women''s and Children''s Hospital, Halkkent/Mersin, Ministry of Health, Turkey;3. Department of Endocrinology, D??kap? Y?ld?r?m Beyaz?t Training and Research Hospital, Ministry of Health, Ankara, Turkey;4. Department of Nuclear Medicine, D??kap? Y?ld?r?m Beyaz?t Training and Research Hospital, Ministry of Health, Ankara, Turkey
Abstract:PurposeTo evaluate the efficacy of apparent diffusion coefficient (ADC) calculation in differentiation between malignant and benign thyroid nodules.Methods and materialsA prospective study was conducted in 52 patients. Diffusion-weighted echoplanar imaging was performed and b factors were taken as 0 and 400 s/mm2.ResultsThe mean ADC value for malignant thyroid nodules was 0.829±0.179×10?3 mm2/s and that for benign thyroid nodules was 1.984±0.482×10?3 mm2/s. The mean ADC value for malignant nodules was significantly lower than that for benign nodules (P=.0001).ConclusionADC value calculation is an effective method in differentiation of malignant thyroid nodules from benign ones.
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