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| 硫酸镁辅助治疗顽固性癫癎72例 | |
| 引用本文： | 李德香,闫士广,李学松,李仁祧,李茂绪,车峰远.硫酸镁辅助治疗顽固性癫癎72例[J].医药导报,2001,20(2):95-96. |
| 作者姓名： | 李德香 闫士广 李学松 李仁祧 李茂绪 车峰远 |
| 作者单位： | 1. 山东省临沂医学专科学校 2. 山东省临沂卫生学校 3. 山东省立医院 4. 山东省临沂市人民医院 |
| 基金项目： | 山东省教委1998年计划内资助课题(J98k71)。 |
| 摘 要： | 目的探讨硫酸镁辅助治疗顽固性癫癎的剂量、方法及疗效。方法治疗组72例，用25%硫酸镁10mL静脉滴注，或用16.5%硫酸镁10mL口服。对照组36例给予常规抗癫癎药物，卡马西平或苯妥英钠加苯巴比妥或氯硝西泮加用γ-氨基丁酸等治疗。结果治疗组有效率87.5%，对照组有效率44.4%，两组比较经统计学分析P＜0.01，差异极显著。结论硫酸镁联合一线抗癫癎药治疗顽固性癫癎的方法简单易行，具有良好效果。 |
| 关 键 词： | 硫酸镁 癫癎，顽固性 卡马西平 |
| 文章编号： | 1004-0781(2001)02-0095-02 |
| 修稿时间： | 2000年4月14日 |
The Effectiveness of Magnesium Sulfate in Treatment of Intractable Epilepsy:A report of 72 Cases |
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| LI De-xiang,YAN Shi-guang,LI Xue-song,LI Ren-tiao,LI Mao-xu,Che Feng-yuan.The Effectiveness of Magnesium Sulfate in Treatment of Intractable Epilepsy:A report of 72 Cases[J].Herald of Medicine,2001,20(2):95-96. | |
| Authors: | LI De-xiang YAN Shi-guang LI Xue-song LI Ren-tiao LI Mao-xu Che Feng-yuan |
| Abstract: | Objective:To determine the dosage,method and effectiveness of using magnesium sulfate for treating the intractable epilepsy.Methods:72 cases were allocated to treatment group and 36 to control group. For those in the treatment group,either 10 mL of 25% MgSO4 was administered by intravenous drip or 10 mL of 16.5% MgSO4 by oral intake once per day,in addition to the use of the commonly used antiepilepsy drugs. For those in the control group,the commonly used antiepilepsy drugs such as tegretol,sodium phenytoin,luminal or γ-Aminobutyric Acid were employed.Results:The improvement rate in the treatment group was 87.50%,higher than that (44.44%) in the control group (P＜0.01).Conclusion:Using magnesium sulfate in conjunction with the antiepilepsy drugs is a simple yet effective regime for the treatment of the intractable epilepsy. |
| Keywords: | Magnesium Sulfate Intractable epilepsy Carbamazepine |
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