淋巴结切除数目对无淋巴结转移的结直肠癌患者预后的影响

目的 探讨淋巴结阴性的结直肠癌患淋巴结切除数目与预后的关系。方法 分析42例无显微镜下淋巴结转移的结直肠癌手术患的临床病理资料，将他们按淋巴结切除数目分为A组(50枚或以下)和B组(50枚以上)，用Kaplan-Meier方法计算5年生存率，用χ^2检验两组间的差异。结果 B组5年生存率为100％，较A组(78．4％)明显增加，P=O．027；A组患肿瘤复发5例，其中5年内死亡3例；而B组患无肿瘤复发和死亡。结论 对无显微镜下淋巴结转移的结直肠癌患。尽量切除全数淋巴结可明显延长患的存活时间。

Effect of number of resected lymph node on the prognosis of patients with node-negative colorectal cancer

Objective To evaluate the long term effect of the number of resected lymph nodes on the prognosis of patients with node negative colorectal cancer. Method Fourty two patients with colorectal cancer were surgically treated and pathology revealed no microscopic nodal involvement. These patients were divided into two groups based on the number of harvested lymph nodes. The prognosis was analyzed retrospectively. Results The 5 year survival rate of the patients with more than 50 harvested lymphatic nodes was significantly higher than that with 50 or less than 50 harvested nodes (100% vs 78 4%,P=0 027). Recurrence occurred in 5 cases and 3 cases died within 5 years in the patients with 50 or less than 50 harvested nodes, while no recurrence and death occurred in the patients with more than 50 harvested nodes. Conclusion Prophylactic lymph node dissection can potentially prolong the survival time of the patients with node negative colorectal cancer.