| 基因盒-整合子系统介导细菌多重耐药的研究进展 |
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| 引用本文： | 吴志鹃,黄永茂. 基因盒-整合子系统介导细菌多重耐药的研究进展[J]. 国外医药(抗生素分册), 2010, 31(1): 34-37 |
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| 作者姓名： | 吴志鹃 黄永茂 |
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| 作者单位： | 泸州医学院附属医院感染科,泸州,646000 |
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| 摘 要： | 基因盒-整合子系统是一种可移动基因元件，可捕获表达耐药基因，并通过质粒或转座子在细菌中水平传播。现就整合子的发现、结构、分类；整合子对基因盒的捕获、表达；整合子与细菌耐药性的关系以及整合子的检测等方面进行综述。
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| 关 键 词： | 整合子 基因盒 细菌 耐药性 |
Research Progress On Bacterial Multidrug Resistance Mediated By Integrons |
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| WU Zhi-juan,HUANG Yong-mao. Research Progress On Bacterial Multidrug Resistance Mediated By Integrons[J]. world notes on antibiotics, 2010, 31(1): 34-37 |
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| Authors: | WU Zhi-juan HUANG Yong-mao |
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| Affiliation: | Department of Infection;The Affiliated Hospital of Luzhou Medical College;Lu Zhou 646000;China |
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| Abstract: | Integrons are mobile genetic elements that can capture and express diverse resistance genes, and are able to transfer laterally into a wide range of bacteria through plasmids and transposons. This paper reviews the discovery, structure and classification of integrons. It also summarizes the capture and expression of gene cassettes by integrons, the relationship between integrons and drug resistance, as well as the detection of integrons. |
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| Keywords: | integrons gene cassette bacteria resistance |
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