得保松和甲氨蝶呤联合注射治疗婴幼儿血管瘤67例

目的：探讨治疗婴幼儿血管瘤有效和创伤小的方法。方法：婴幼儿血管瘤患者67例,年龄2～15月,头面部42例,颈部6例,躯干16例,四肢3例;增生期58例,消退期9例;所有病例使用瘤体间质内注射得保松与甲氨蝶呤混合液。结果：所有病例均经过0.5～2年的随访,治愈26例,基本治愈33例,好转7例,无效1例。结论：得保松联合甲氨蝶呤局部注射疗法适合于大多数血管瘤的治疗,能够控制血管瘤的生长,促进其消退,而且治疗容易,创伤小,无明显副作用。

Local Injection of Diprospan with Methotrexate(MTX)in the management of infantile hemangioma

Objective To study the therapy of infantile hemangiomas with effectively and minimally invasive. Methods A total of 67 patients with hemangiomas were treated by the same surgeon from September,the study ranging in age from 2 months to 15 months,among the 67 patients,42 hemangiomas were located on the head and face,6 on the neck,16 on the trunk,and 3 on the extremities.According to Mulliken biological cataloge,58 hemangiomas in growth stage and 9 in involution stage. Apply the injection of Diprospan with MTX in interstitial tissue of the hemangioma. Results All patients were followed up for a half year to 2 years.Follow up results showed that 26 patients were cured,33 were greatly improved,7 were partly improved,and 1 patient was noobvious improvement. Conclusions Local injection of Diprospan with MTX is suitable to for the treatment of most infantile hemangiomas,which can well control the growth of the lesion and improve to involute.1t＇s a easy,minimally jnvasive approach to treat hemangiomas and also provides an barely effect.