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甲基强的松龙冲击治疗小儿难治性肾病综合征(附16例临床报告)
引用本文:孙玲娣,刘成志,毕文术,陈莉娃. 甲基强的松龙冲击治疗小儿难治性肾病综合征(附16例临床报告)[J]. 哈尔滨医科大学学报, 1992, 0(1)
作者姓名:孙玲娣  刘成志  毕文术  陈莉娃
作者单位:哈尔滨医科大学一院儿科(孙玲娣,刘成志,毕文术),哈尔滨医科大学第四医院儿科(陈莉娃)
摘    要:本文报告应用甲基强的松龙冲击疗法治疗小儿难治性肾病综合征16例,其中14侧冲击治疗前口服强的松每日2mg/kg×8周,无明显疗效;另2例为勤复发型原发性肾病,此次入院后即进行冲击治疗。冲击用甲基强的松龙,剂量为每次15mg/kg或每次20mg/kg。治疗结果9例完全缓解,6例部分缓解,仅1例无效。此结果表明甲基强的松龙冲击治疗难治性肾病综合征有显著疗效。

关 键 词:甲基强的松龙  冲击疗法  难治性肾病综合征

Treatment of Refractory Nephrotic Syndrome in Children with ''''Pulse ''''Methylprednisolone Therapy(A Clinical Report of 16 Cases)
Sun Lingdi et al. Treatment of Refractory Nephrotic Syndrome in Children with ''''Pulse ''''Methylprednisolone Therapy(A Clinical Report of 16 Cases)[J]. Journal of Harbin Medical University, 1992, 0(1)
Authors:Sun Lingdi et al
Abstract:Sixteen children with refractory nephrotic syndrome were treated with'pulsel methylprednisolone therapy(PMT). Of those 14 were treated with prednisone 2mg/kg/day for 8 weeks without obvious curative effect before application of PMT, and the other 2 diagnosed as frequently recurrent type of primary nephrosis were treated with PMT immediately after admission, methylprednisolone 15mg/kg or 20mg/kg diluted in glucose injection was administrated by intravenous drip. The results revealed that 9 cases were relieved completely, 6 cases partially and 1 case was ineffective. The results make it clear that PMT has remarkable effect in treatment of refractory nephrosis.
Keywords:Methylprednisolone  'Pulse'therapy  Refractory nephrotic syndrome
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