聚焦超声治疗外阴尖锐湿疣临床及病理分析

目的:探讨运用聚焦超声治疗外阴尖锐湿疣的临床疗效.方法:经病理活检证实的外阴尖锐湿疣患者108例,随机等数量分配至超声组和激光组(对照组),利用海极星(Seapostar)超声波妇科治疗仪进行治疗,激光组采用CO2激光治疗机进行治疗,观察两种方法治疗前后患者症状和体征变化.并取超声治疗前后的疣体作病理活检,由此评价分析聚焦超声治疗外阴尖锐湿疣的临床疗效和病理变化.结果:1、超声组中经1次超声扫描即痊愈者49例,有效率为90.7%(49/54).激光组的治疗有效率为68.5%(37/54).两组治疗效果有极显著性差异(P＜0.01).2、外阴尖锐湿疣疣体经聚焦超声治疗后的大体病理与组织病理变化明显,主要表现为萎缩现象.结论:治疗剂量的聚焦超声治疗外阴尖锐湿疣疗效肯定、治愈率高、安全、无创,可作为临床治疗的方法之一.

Clinical and pathological analysis of vulval condyloma acuminatum treated with focused ultrasound

Objective:To investigate the clinical curative effect of focused ultrasound on vulval condyloma acuminatum.Methods:108 cases of vulval condyloma acuminatum confirmed by pathology were randomly divided into two groups with the same number in each group:ultrasound group and laser group(controls).54 cases in the ultrasound group were treated with focused ultrasound,other 54 cases underwent laser treatment.The symptoms and local changes of the patients were observed before and after the treatment.The warts were obtained for pathological analysis to evaluate the efficacy of focused ultrasound treatment.Results:1.In the ultrasound group,49 cases recovered after the first treatment,the efficacy rate was 90.7%(49/54),while in the laser group,the rate was 68.5%(37/54).There was significant difference between the two groups(P<0.01).2.The pathologic changes of vulval condyloma acuminatum were evident after the focused ultrasound treatment,and the main change was expressed as atrophy.Conclusions: Focused ultrasound is effective,safe and non-invasive,which can be used as one of the methods for the treatment of vulval condyloma acuminatum.