抵抗素和高敏C-反应蛋白在突发性耳聋中的临床意义

目的探讨突发性耳聋患者血清抵抗素和高敏C-反应蛋白（hs-CRP）的含量变化，及其在突发性耳聋发生过程中的作用和意义。方法检测102例突发性耳聋组、35例其他疾病对照组和30例健康对照组的血清抵抗素和hs-CRP含量，并比较治疗前后血清抵抗素和hs-CRP含量的变化。结果突发性耳聋组患者治疗前血清抵抗素和hs-CRP含量较其他疾病对照组和健康对照组显著升高（P〈0．01）；治疗后突发性耳聋组患者抵抗素和hs-CRP含量明显降低。突发性耳聋患者血清抵抗素和hs-CRP含量呈正相关（r=0．65，P〈0．01）。结论血清抵抗素和hs-CRP含量的变化与突发性耳聋病情严重程度密切相关。

The influence of the upper thoracic block on the consumed oxygen and ischemia in the coronary disease of elderly patients

Objective To evaluate the upper thoracic block on the consumed oxygen and ischemia dergoing lobectomy were randomized to receive either combined general-epidural anesthesia(GEA group,n=25)or general anesthesia(GA group,n=25).To observe systolic pressure(SBP),heart rate(HR),ST section and T wave before anesthesia(T1),after epidural infusion 20 minutes(T2),intubated the trachea(T3),at the end of operation(T4),drew the trachea(T5),after drew the trachea 30minutes(T6).Results SBP,HR,RPP were significantly increased in GA groupas compared with those in GEA group at L3,L5,T6(P＜0.05),The change of ST section and T wave were significantly improved in GEA group as compared with those in GA group at T2,B3,T4,T5,T6(P＜0.05).Conclusion The influence of the upper thoracic block can decrease the consumed oxygen and ischemia, improve the myocardial ischemia in the coronary disease patient undergoing lobectomy, to reduce the complication of the coronary disease patient in the perioperative.