| 睾酮经皮吸收膜剂的研究 |
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| 引用本文： | 杨鹏晖 袁和亮. 睾酮经皮吸收膜剂的研究[J]. 中国医药工业杂志, 1994, 25(3): 112-114 |
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| 作者姓名： | 杨鹏晖 袁和亮 |
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| 作者单位： | 上海市计划生育科研所国家药具重点实验室 |
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| 摘 要： | 睾酮经皮吸收膜剂选用硅橡胶为骨架材料，由铝塑背衬层、含药模层、压敏胶层、剥离纸组成。并用ＨＰＬＣ方法检测睾酮体外释药及经皮渗透速率，结果表明其离体渗透符合零级动力学过程。
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| 关 键 词： | 睾酮，经皮给药系统，促进剂，硅橡胶，经皮渗透 |
STUDIES ON TRANSDERMAL DRUG DELIVERY SYSTEM OF TESTOSTERONE |
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| YANG Peng-Hui, YUAN He-Liang,ZHANG Xiao-Dong,SHI Hui. STUDIES ON TRANSDERMAL DRUG DELIVERY SYSTEM OF TESTOSTERONE[J]. , 1994, 25(3): 112-114 |
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| Authors: | YANG Peng-Hui YUAN He-Liang ZHANG Xiao-Dong SHI Hui |
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| Abstract: | A transdermal delivery system contaning testcoterone was prepared. In vitro release and skin permeation profiles of testosterone from various TDS formulations were studied by the HPLC method to show that the former followed Higuchi equation and the latter. zero-order kinetics. |
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| Keywords: | testosterone transdermal drug delivery system enhancer silicone rubber. skin permeation |
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