| 兔角膜碱烧伤角膜小体形态学及组织化学研究 |
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| 引用本文： | 燕振国,张晓春.兔角膜碱烧伤角膜小体形态学及组织化学研究[J].眼外伤职业眼病杂志,1996(1). |
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| 作者姓名： | 燕振国 张晓春 |
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| 作者单位： | 解放军兰州军区总医院眼科 730050 |
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| 摘 要： | 用1mol/L NaOH溶液造成兔角膜碱烧伤模型.对烧伤后不同时期角膜基质层角膜小体(CC)及其周边粘多糖(MP)变化进行了形态学及组织化学研究.结果发现:(1)烧伤后CC胞浆增多,其周边MP明显减少;(2)第7天时,CC全部转化为纤维母细胞,周边MP超过正常角膜组织;(3)14天时,轻度烧伤中基质层有极少CC出现,周边MP亦趋于正常.(4)这种变化与烧伤程度呈平行关系,与创伤的恢复呈反比关系.
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| 关 键 词： | 角膜小体 纤维母细胞 粘多糖 |
Morphological and histochemical studies on corneal corpuscle of alkali burned corneal stroma in rabbit. |
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| Yon Zhenguo,et al..Morphological and histochemical studies on corneal corpuscle of alkali burned corneal stroma in rabbit.[J].Journal of Injuries and Occupational Diseases of the Eye with Ophthalmic Surgeries,1996(1). |
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| Authors: | Yon Zhenguo |
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| Institution: | Yon Zhenguo,et al. Department of Ophthalmology,General Hospital of Lanzhou Millitary. Lanzhou. 730050. |
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| Abstract: | The model of alkali burned cornea in rabbit made by Imol/L NaOH solution. The morphological and his-tochemical changes of corneal crpusle (CC) and mu-copolysaccharide (MP) were studied using electromi-croscope and Lectin-Fluorescene probe. The results were: (1) 1-3 days after the burn,the cytoplasma of CC increased,while the MP decreased; (2)4-7 days later,all of CC transformed to fibroblasts and MP higher than it in normal cornea; (3)Until 8-14 days,a few of CC occurred in low-grade burned stroma ,the MP tend to normal. (4)These changes related to the degree of the burn and recovery of trauma. |
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| Keywords: | Corneal copuscle Fibroblast Mucopolysaccharide |
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