婴幼儿轮状病毒肠炎肠道微生态学改变

目的：研究婴幼儿轮状病毒肠炎肠道微生态的改变。方法：选择腹泻组（39例轮病毒肠炎患儿）和对照组（30例健康婴幼儿），对他们的肠道菌群进行定量测定，其中20例轮状病毒肠炎患儿，对他们肠道菌群进行动态定量分析。结果：轮状病毒肠炎患儿肠道菌群中双歧杆菌，拟杆菌，乳杆菌和肠球菌数量较对照组显著下降，肠杆菌在菌群中所占比例相对升高，在发病早期即出现肠菌群紊乱，随着腹泻症状消退，肠菌群失调症状逐渐纠正，而且厌氧菌上升速度较快，结论：轮状病毒肠炎患儿伴有明显的肠菌群失调，且菌失调的程度与临床病情及脱水程度有关。

Alteration in intestinal microecology in infants with rotavirus eneritis

Objective: To study the alteration in the intestinal microecology in the infants with rotavirus enteritis. Methods: The quantitative measurement was used for the intestinal flora in 39 infants with rotavirus enteritis diarrhea (compared with 30 healthy infants). The dynamic quantitative analysis was made in the alteration in the intestinal flora in 20 of 39 infants. Results: Compared with 30 healthy infants, the number of bifidobacteria, bacteroides, lactobacillus and enterococcus obviously reduced in the intestinal flora in the infants with rotavirus enteritis, with a relative rise in the proportion of entrobacillus in the flora. In the early period of the disease occurred intestinal dysbacteriosis. With the disappearance of diarrhea symptoms, dysbacteriosis was gradually redressed and anaerobes increased quickly. Conclusion: The infants with rotavirus enteritis is associated with marked intestinal dysbacteriosis and the dysbacteriosis severity is related to the clinical condition and dehydration.