| 大肠癌证候及其现代生物医学内涵研究 |
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| 引用本文： | 闫霞,郑佳露,胡兵.大肠癌证候及其现代生物医学内涵研究[J].世界科学技术-中医药现代化,2017,19(7):1253-1257. |
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| 作者姓名： | 闫霞 郑佳露 胡兵 |
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| 作者单位： | 上海中医药大学附属龙华医院，肿瘤科 上海 200032；上海市中医药研究院，中医肿瘤研究所 上海 200032,上海中医药大学附属龙华医院，肿瘤科 上海 200032,上海中医药大学附属龙华医院，肿瘤科 上海 200032；上海市中医药研究院，中医肿瘤研究所 上海 200032 |
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| 基金项目： | 国家自然科学基金（81473625）：藤龙补中汤对M2型肿瘤相关巨噬细胞分化及其介导大肠癌转移作用研究，负责人：胡兵；上海市中医药事业发展三年行动计划（ZY3-CCCX-3-3025）：中医药靶向肿瘤相关巨噬细胞防治大肠癌转移研究，负责人：胡兵；上海市科技支撑项目（16401902500），促大肠癌细胞衰老新药藤龙补中颗粒临床前研究，负责人：胡兵。 |
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| 摘 要： | 大肠癌（Colorectal cancer，CRC）可以归属于多个中医病证，临床表现复杂，可以呈现多种证候。现代研究初步揭示大肠癌证候与病理、细胞类型、分期及预后有密切关系；手术、化疗等现代治疗对大肠癌的证候有一定的影响；现代中医同时对大肠癌湿热蕴结、瘀血内阻、脾气亏虚、气血两虚、肝肾阴虚等证候的生物医学内涵进行了广泛的研究。这些研究对大肠癌证候的客观化和规范化研究有积极的意义。
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| 关 键 词： | 大肠癌 中医 证候 生物标志 病理 |
| 收稿时间： | 2017/3/15 0:00:00 |
| 修稿时间： | 2017/7/16 0:00:00 |
TCM Syndromes (Zheng) of Colorectal Cancer and Its Biomedical Basis |
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| Yan Xi,Zheng Jialu and Hu Bing.TCM Syndromes (Zheng) of Colorectal Cancer and Its Biomedical Basis[J].World Science and Technology-Modernization of Traditional Chinese Medicine,2017,19(7):1253-1257. |
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| Authors: | Yan Xi Zheng Jialu and Hu Bing |
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| Institution: | Department of Oncology, Longhua Hospital, Shanghai University of Traditional Chinese Medicine,Shanghai 200032, China; Institute of Traditional Chinese Medicine in Oncology, Shanghai Academy of Traditional Chinese Medicine, Shanghai 200032, China,Department of Oncology, Longhua Hospital, Shanghai University of Traditional Chinese Medicine,Shanghai 200032, China and Department of Oncology, Longhua Hospital, Shanghai University of Traditional Chinese Medicine,Shanghai 200032, China; Institute of Traditional Chinese Medicine in Oncology, Shanghai Academy of Traditional Chinese Medicine, Shanghai 200032, China |
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| Abstract: | Colorectal cancer (CRC) belongs to multiple diseases of traditional Chinese medicine (TCM). CRC can exhibit sophisticated clinical manifestations and various TCM syndromes (Zheng). Modern studies have revealed that syndromes (Zheng) of CRC are related to pathological characteristics, cell types, staging and prognosis. Surgery, chemotherapy and other modern treatments can influence the manifestations of syndromes (Zheng) of CRC. Modern TCM doctors have extensively studied the biomedical basis of syndromes (Zheng) of CRC, including accumulation of damp-heat (Shi-Re- Yun-Jie), blood stasis (Yu-Xue-Nei-Zu), spleen (Pi) deficiency (Pi-Qi-Kui-Xu), deficiency of qi and blood (Qi-Xue- Liang-Xu), deficiency of yin of liver (Gan) and kidney (Shen) (Gan-Shen-Yin-Xu) and other syndromes (Zheng). These investigations may contribute to the objective and standardization study of syndromes (Zheng) in CRC. |
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| Keywords: | Colorectal cancer traditional Chinese medicine traditional Chinese medicine syndromes (Zheng) biomarker pathology |
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